Our Mission
The Silverstein Dream Foundation is a nonprofit organization with a unique mission to support diabetes research and address chronic conditions associated with diabetes and its inflammatory effects.
As we embark on our mission to fund innovative treatments, we have identified three key areas of focus:
1.Type 1 Action. Supporting Academic Research and access to Clinical Trials - We organize social events and fundraising initiatives to advance groundbreaking research.
2.Implementing Diabetes Prevention Programs - We educate and empower underrepresented communities on the importance of early detection and proper nutrition to prevent diabetes progression and diagnosis.
3.Strategic Investments in Early and Growth Stage Companies - We invest in promising innovations that measurably reduce the incidence, progression, and complications of diabetes—prioritizing early detection, prevention, and equitable access to technology-enabled care.
By combining these efforts, we aim to drive meaningful progress and bring hope to those affected by this disease.
Diabetes in the United States
Current estimates show that 1 in 3 Americans will develop diabetes sometime in their lifetime. 1 Diabetes is a chronic (long-lasting) health condition that affects how the body turns food into energy and results in too much sugar in the bloodstream. Over time, this can cause serious health problems and damage vital organs. Most people who have diabetes have a shorter life expectancy than people without the disease.
Diabetes in youth
About 352,000 Americans under age 20 are estimated to have diagnosed diabetes, approximately 0.35% of that population.
In 2017–2018, the annual incidence of diagnosed diabetes in youth was estimated at 18,200 with type 1 diabetes, 5,300 with type 2 diabetes.
Quick Facts
• 38 million people of all ages (about 11.6% of the population) have diabetes.
• 98 million adults (38%) have prediabetes, blood sugar levels that are higher than normal but not high enough to be diagnosed as diabetes.
• Diabetes complications are increasing for young adults aged 18 to 44 and middle-aged adults aged 45 to 64.
• Diabetes is more common among American Indian or Alaska Native, non-Hispanic Black, Hispanic, and Asian people than non-Hispanic White people.
• Nearly 1 in 5 adolescents aged 12 to 18 and 1 in 4 young adults aged 19 to 34 have prediabetes.
Our Work
Diabetes Focused Research
Advancing Cure-Focused Research
Our highest priority is to accelerate the discovery of a biological cure for diabetes, particularly type 1 diabetes.
We support leading institutions and collaborative initiatives, including the Diabetes Research Institute and The Cure Alliance, by funding high-impact clinical trials and breakthrough research currently in development.
Our approach focuses on:
* Bridging the gap between laboratory discoveries and patient access
* Supporting clinical-stage innovations with the highest potential for cure
* Accelerating timelines to bring life-changing therapies to those in need
Our mission is clear: to help end the burden of chronic, debilitating, and life-threatening diseases through scientific advancement.
Diabetes Prevention Program
Our mission is to transform the healthcare system by redefining how we treat and prevent all types of diabetes.
Two Key Interventions
Early detection of type 1 diabetes antibodies in younger individuals (ages 5-18) to help prevent the onset of type 1 diabetes.
Testing individuals diagnosed with type 1 diabetes, type 2 diabetes, and prediabetes by analyzing inflammatory biomarkers to assess risks.
This approach aims to support optimal health and prevent future diabetes-related complications such as cardiovascular disease, kidney disease, retinopathy, and neuropathy.
Impact-D: Investing in the Future of Diabetes Prevention and Care
The Silverstein Dream Foundation's Impact-D Program is a mission-driven initiative that supports innovative companies and technologies working to prevent diabetes, improve care, and reduce life-changing complications.
By combining philanthropic capital, strategic support, and healthcare expertise, we help accelerate solutions that have the potential to improve health outcomes and expand access to care for millions of people affected by diabetes.
Our Investment Approach
We support early-stage and growth-stage innovations that demonstrate:
Strong scientific and clinical foundations
Clear patient and public health benefits
Scalable and accessible solutions
Potential to reduce the burden of diabetes worldwide
As a nonprofit organization, every Impact-D investment and partnership is made in furtherance of our charitable mission: advancing public health, accelerating innovation, and improving the lives of people living with or at risk of diabetes.
Our vision is simple: to help bring transformative diabetes solutions to patients faster while creating lasting impact for future generations.
Our Focus Areas
Prevention & Early Detection – Identifying risk earlier and helping people prevent disease progression.
Diabetes Management – Improving daily care, monitoring, and patient outcomes.
Complications Prevention – Advancing solutions for diabetic retinopathy, kidney disease, cardiovascular disease, neuropathy, and other diabetes-related complications.
Access to Care – Supporting scalable healthcare models that improve access, education, and health equity.
Be part of our Diabetes Prevention Program!
